Our client one the largest pharmaceutical companies in USA is looking for a Scientist - II @ Boston, MA.

Job Title: Scientist - II

Location: Onsite - Boston, MA 02115

Hours: M-F 8:00am - 5:00pm

Qualifications:

Education Requirement:

• BS/BA degree in biochemistry, biophysics or a related discipline with a minimum of 3-5 years industry experience; or a MS degree in biochemistry, biophysics or a related discipline with 2 or more years of industry experience, preferably with a focus on assay development and compound profiling within a drug discovery environment.

Required Skills:

• Candidate should have basic knowledge of biochemistry, biophysics and molecular biology

• Candidate should have prior experience with basic biochemical and/or biophysical techniques

• Candidate should be highly motivated, driven, and willing to take the initiative to learn new scientific methodologies

• Candidate should be a strong team player

• Candidate should have excellent oral and written communication skills

• Candidate should be comfortable using a PC computer and proficient in Windows-based operating systems and basic applications, such as spreadsheets and databases

• Experience in the use of automated liquid handlers such as Echo, Bravo, Biomek, or Hamilton and data analysis and presentation software such as TIBCO Spotfire, Excel and PowerPoint.

Preferred Attributes:

• Proven ability to independently design, develop and implement biochemical and biophysical screening assays using detection modalities such as: TR-FRET, FP, LC-MS, radiochemical, surface plasmon resonance (BIAcore), fluorescence-based thermal shift (TdF), and/or isothermal titration calorimetry (ITC).

• Hands-on experience performing steady-state and transient-state kinetic experiments to study enzymes and inhibitors.

• Direct experience in recombinant protein expression using bacteria, insect (baculovirus) and/or mammalian cell-based systems and purification using automated chromatographic separation systems.

Responsibilities:

This is an exciting opportunity in the Biochemistry and Biophysics Group within the Department of Pharmacology at our client's Boston location.

The successful candidate is expected to:

• Develop and/or run quantitative biochemical and biophysical assays to support identification, characterization, and optimization of small molecule ligands from high throughput screening campaigns and medicinal chemistry efforts.

• Conduct biochemical and biophysical studies to elucidate the modes of ligand interaction and mechanisms of action on target proteins.

If this is a role that interests you and you’d like to learn more, click apply now and a recruiter will be in touch with you to discuss this great opportunity. We look forward to speaking with you!

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ManpowerGroup® (NYSE: MAN), the leading global workforce solutions company, helps organizations transform in a fast-changing world of work by sourcing, assessing, developing, and managing the talent that enables them to win. We develop innovative solutions for hundreds of thousands of organizations every year, providing them with skilled talent while finding meaningful, sustainable employment for millions of people across a wide range of industries and skills. Our expert family of brands – Manpower, Experis, Talent Solutions, and Jefferson Wells – creates substantial value for candidates and clients across more than 75 countries and territories and has done so for over 70 years. We are recognized consistently for our diversity - as a best place to work for Women, Inclusion, Equality and Disability and in 2022 ManpowerGroup was named one of the World's Most Ethical Companies for the 13th year - all confirming our position as the brand of choice for in-demand talent.

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