Position Summary

The highly collaborative McCabe laboratory takes an interdisciplinary approach to study the mechanisms involved in the gut-bone signaling axis and to identify therapeutics that target the gut to treat and prevent osteoporosis. The successful applicant will utilize cell culture, mouse models, and human studies to identify signals and factors mediating bone health under standard, aging, and disease conditions. They will also be involved in laboratory leadership (training of students), interacting with other faculty, and assisting in developing proposals and manuscripts. Responsibilities will include:

• Protein/RNA/DNA extractions and analyses, RT-PCR, assays (serum measures, ELISA, cytokine assays), histomorphometry, micro-computed tomography measures, etc. to generate data for research projects.
• Sterile cell culture for experiments and assays
• Excellent record maintenance including methods used, adjustments to protocols, sample location, sample measures, etc.
• Assistance in compiling test results and preparing information for reports and publications. Use of statistical software (e.g. GraphPad Prism) to analyze, graph, and prepare data for figures/presentation.
• Ability to develop trouble shoot new methods and to ensure that methods are operational and functional.
• Use and calibration of research equipment (with training) such as mass spectrometers; vacuum systems; computers and related software; etc.
• Ordering supplies and experimental research animals and maintains and prepares solutions, animals and other materials to prepare for experimental procedures.
• Collection and preparation of materials and data necessary for performing experiments.
• Supervision and instruction of students in the performing basic research techniques.
• Completing duties normally associated with a Research Technologist I or similar lower-level classifications in order to complete research projects.

The hourly rate of the selected candidate for this role will be set based on multiple factors, including but not limited to, experience, education, specialized skills, training, and internal equity. Your total compensation goes beyond scale, total compensation provided by Michigan State University and the McCabe Lab includes health insurance, generous leave and retirement contributions. This position funded for one (1) year from date of hire with extension contingent on satisfactory performance and available funding. The duties to be performed by this position require regular in-person presence in East Lansing, MI. This position will require successful completion of standard background checks.

Department Statement:

The Department of Physiology and Division of Pathology Division have significant teaching and research missions. The position works with a global community of internationally recognized scholars from diverse nationalities, ethnicities, and backgrounds; two large undergraduate majors (Physiology and Neuroscience) with approximately 1,200 majors combined; the Molecular, Cellular, and Integrative Physiology (MCIP) graduate program, popularly combined with professional degrees (MD, DO, DVM); and vibrant research programs in areas such as cancer biology, cardiac pathophysiology, diabetes and obesity, gastrointestinal health and disease, immunity and tissue inflammation, musculoskeletal diseases, molecular metabolism and disease, and neuroscience. The discipline of physiology is uniquely positioned among the biomedical sciences to span the gulf between exploring the most fundamental aspects of biology and the most practical and applied problems of human and animal health. Faculty in the Physiology Department at Michigan State University work to understand how the vast array of molecular and cellular events successfully integrates to define the phenomenon of