Scientist - Medicinal Chemistry

Requisition ID: 5833

Location:

La Jolla, CA, US

Do you want to join a team where the mission is meaningful, the challenges are complex, and you can directly see the results of your hard work? Lundbeck is a global biopharmaceutical company focusing exclusively on brain health. With more than 70 years of experience in neuroscience, we are committed to improving the lives of people with neurological and psychiatric diseases. Lundbeck employees are inspired and driven by our purpose to advance brain health and transform lives. As Lundbeck’s North American hub for early-stage drug discovery, the Lundbeck La Jolla Research Center positions our company to deliver transformative treatments for brain disease. Join us on our journey of discovery!

SUMMARY

Lundbeck La Jolla Research Center, Inc. (LLJRC), a discovery research arm of H. Lundbeck A/S, is seeking a motivated, enthusiastic synthetic chemist to support preclinical stage programs in the portfolio and make transformative medicines for patients with brain diseases. In this role, the successful candidate will be responsible for working with project teams to design and synthesize first-in-class small molecules and progress them to the drug candidate stage.

ESSENTIAL FUNCTIONS:

• Contribute to multi-disciplinary project teams in developing innovative, high-quality small molecule therapeutics

• Independently and with a team design drug-like compounds for synthesis, in line with project strategy, incoming data, and knowledge of in vitro and in vivo DMPK and physicochemical properties

• Employ state-of-the-art techniques and synthetic methods to design, execute, optimize, and analyze multi-step synthetic strategies

• Interact directly with Contract Research Organizations (CROs)

• Identify opportunities to access state-of-the-art chemistry capabilities and infrastructure, and maintain lab instrumentation

• Contribute to objective setting for project team

• Train associate scientists, research associates, and interns

• Responsible for data analysis, preparation of reports, and presentations to project teams, site, and global scientific leadership

• Contribute to publications in peer-reviewed journals, present work at scientific conferences, and prepare patent applications

• Approximately 75% of work is lab-based and focuses on development and execution of synthetic strategies towards drug-like small molecule compounds

REQUIRED EDUCATION, EXPERIENCE, and SKILLS:

• Ph.D. in organic chemistry or related area, or MS with 9+ years experience or a BS with 12+ years experience

• Demonstrated broad knowledge of and experiencein planning, developing, and enabling multistep organic syntheses

• Expertise in developing new transformations and in analyzing and optimizing reactions

• Innovative, rigorous, and can devise and execute successful synthetic chemistry strategies

• Ability to develop, implement, and clearly communicate chemistry strategies to team, management, and collaborators

• Excellent collaboration, communication, and presentation skills.

• Both effective team player and strong individual contributor, flexible, and able to handle multiple tasks and deliver high quality results under tight timelines

• Thrives in a team environment of shared goals and responsibilities

PREFERRED EDUCATION, EXPERIENCE, and SKILLS:

• Experience in medicinal chemistry or pharmaceutical drug discovery/development

• HPLC/UPLC - MS analytical and preparative-scale chromatography experience

• Expertise in cheminformatics systems and methods

• Familiarity working with Contract Research Organizations

• Experience with hit triage, hit-to-lead chemistry, parallel synthesis, and tool identification

TRAVEL:

• Willingness/Ability to travel up to 10% domestically. International travel may be required.

The range displayed is specifically for those potential hires who will work or reside in the state of California, if selected for this role, and may vary based on various factors such as the candidate’s qualifications, skills, competencies and proficiency for the role. Salary Pay Range: $120,000 - $145,000 and eligibility for a 15% bonus target based on company and individual performance. Additional benefits for this position include flexible paid time off (PTO), health benefits to include Medical, Dental and Vision and company match 401k. Additional benefits information can be found on our site (https://www.lundbeck.com/content/dam/lundbeck-com/americas/united-states/careers/Lundbeck_Benefits_Summary.pdf) . Applications accepted on an ongoing basis.#LI-LM1

Why Lundbeck

Lundbeck offers a robust and comprehensive benefits package to help employees live well and protect their health, family, and everyday life. Information regarding our benefit offering can be found on theU.S. career site (https://www.lundbeck.com/content/dam/lundbeck-com/americas/united-states/careers/Lundbeck_Benefits_Summary.pdf) .

Lundbeck is committed to working with and providing reasonable accommodations to disabled veterans and other individuals with disabilities during our employment application process. If, because of a disability, you need a reasonable accommodation for any part of the application process, please visit theU.S. career site (https://www.lundbeck.com/us/careers/your-job/eeo-accommodations-policy) .

Lundbeck is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status, and any other characteristic protected by law, rule, or regulation. Lundbeck participates in E-Verify (https://www.lundbeck.com/content/dam/lundbeck-com/americas/united-states/careers/E-Verify_Participation_Poster_Eng_Es.pdf) .

About Lundbeck

At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us.

Through cutting edge science and strong partnerships, we develop and market some of the world’s leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology.

The brain health challenge is real. Our commitment is real. Our impact is real.

About Lundbeck

At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us.

Through cutting edge science and strong partnerships, we develop and market some of the world’s leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology.

The brain health challenge is real. Our commitment is real. Our impact is real.